AbstractThe current study attempts to elucidate the effects of drug or substance misuse on students' academic performance that are in the 16-21 age range. Drug and substance addiction has numerous other negative effects, including physiological, psychological, and physical ones that are severely disrupted. They all have adverse effects, both short- and long-term, depending on the drug's composition, dosage, and usage duration. In this study, we want to inform and raise students' awareness of the worst repercussions of drug and substance misuse in addition to elucidating the negative effects of drug and substance abuse on academic performance.