International Journal of Research in Psychiatry

2024, Vol. 4, Issue 1, Part A

Adverse effects of antidepressant medications: A comparative analysis of different classes
Author(s)
Avantika Kampani
Abstract
This review offers a comparative analysis of the adverse effects associated with various classes of antidepressants, and effective strategies to manage their effects in clinical practices. Antidepressant medications, essential for treating depression, display diverse side effect profiles that significantly influence patient adherence and the success of treatment regimens. Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are generally well-tolerated, yet they are frequently associated with sexual dysfunction and weight gain, which can hinder patient compliance. Tricyclic antidepressants (TCAs), known for their efficacy, have a higher incidence of cardio toxic effects and anticholinergic side effects, making them less suitable for certain populations. Monoamine oxidase inhibitors (MAOIs), though effective for treatment-resistant cases, are used less frequently due to the need for dietary restrictions and the risk of severe drug interactions. This review describes mechanism of action of commonly used antidepressants from various classes and stresses on the specific adverse effect profiles of each drug class. Further, we discuss the strategies for managing adverse effects, such as dosage adjustments and switching medications, which play a crucial role in enhancing medication adherence and improving treatment outcomes. This review article aims to equip clinicians with the necessary knowledge to optimize antidepressant therapy by balancing efficacy against potential adverse effects, thereby improving patient well-being and therapeutic success.
Pages: 21-32 | Views: 241 | Downloads: 86


International Journal of Research in Psychiatry
How to cite this article:
Avantika Kampani. Adverse effects of antidepressant medications: A comparative analysis of different classes. Int J Res Psychiatry 2024;4(1):21-32. DOI: 10.22271/27891623.2024.v4.i1a.49
International Journal of Research in Psychiatry

International Journal of Research in Psychiatry

International Journal of Research in Psychiatry
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